CR1 / INSERM
Equipe : Methylation de l’ADN et ARNs non-codants en physiopathologie
Pièce n°: 411
Alain is a researcher (CR1) at INSERM. He received his PhD in 1993 from University Paris 6 in Paris, France. He was recruited by INSERM in 1996 after a post-doctoral study in Institut Curie, Orsay, France. Alain moved to the CGM (Centre de Génétique Moléculaire) at Gif/Yvette, France in 1999 before joining the Claire Francastel’s Lab at the Epigenetic and Cell Fate Unit in 2012.
Laurent FX, Sureau A, Klein AF, Trouslard F, Gasnier E, Furling D, Marie J. New function for the RNA helicase p68/DDX5 as a modifier of MBNL1 activity on expanded CUG repeats. Nucleic Acids Res. 2012 Apr;40(7):3159-71. PMID: 22156369
Sureau A, Saulière J, Expert-Bezançon A, Marie J. CELF and PTB proteins modulate the inclusion of the β-tropomyosin exon 6B during myogenic differentiation. Exp Cell Res. 2011 Jan 1;317(1):94-106. PMID: 20875406
Saulière J, Sureau A, Expert-Bezançon A, Marie J. The polypyrimidine tract binding protein (PTB) represses splicing of exon 6B from the beta-tropomyosin pre-mRNA by directly interfering with the binding of the U2AF65 subunit. Mol Cell Biol. 2006 Dec;26(23):8755-69. PMID: 16982681