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Gaël CASTEL
Bioinformatician (CDD CNRS ERC XCycle)
Equipe : ARNs non-codants, Différenciation et Développement
Téléphone : 0157278929
Pièce n°: 426

Gaël performed his doctoral research on human trophoblast stem cells in the laboratory of Dr. Laurent David at the University of Nantes, where he graduated with a Ph.D. in Cell Biology.
During this period, he moved to Vienna, Austria, where he collaborated with the team of Dr. Nicolas Rivron, working on human blastoids. Involved in multi-omics analyses, he graduated with a university degree in integrative bioinformatics (DUBii 2021) from the University of Paris (now Paris City University).
He joined the Rougeulle lab as a research engineer in bioinformatics to address dosage compensation from a computational perspective.
He enjoys visiting the world and learning about foreign cultures.

SELECTED PUBLICATIONS

  • Castel, G., Meistermann, D., Bretin, B., Firmin, J., Blin, J., Loubersac, S., Bruneau, A., Chevolleau, S., Kilens, S., Chariau, C., Gaignerie, A., Francheteau, Q., Kagawa, H., Charpentier, E., Flippe, L., François-Campion, V., Haider, S., Dietrich, B., Knöfler, M., … David, L. (2020). Induction of Human Trophoblast Stem Cells from Somatic Cells and Pluripotent Stem Cells. Cell Reports, 33(8), 108419. https://doi.org/10.1016/j.celrep.2020.108419
  • Kagawa, H., Javali, A., Khoei, H. H., Sommer, T. M., Sestini, G., Novatchkova, M., Scholte Op Reimer, Y., Castel, G., Bruneau, A., Maenhoudt, N., Lammers, J., Loubersac, S., Freour, T., Vankelecom, H., David, L., & Rivron, N. (2021). Human blastoids model blastocyst development and implantation. Nature. https://doi.org/10.1038/s41586-021-04267-8
  • Meistermann, D., Bruneau, A., Loubersac, S., Reignier, A., Firmin, J., François-Campion, V., Kilens, S., Lelièvre, Y., Lammers, J., Feyeux, M., Hulin, P., Nedellec, S., Bretin, B., Castel, G., Allègre, N., Covin, S., Bihouée, A., Soumillon, M., Mikkelsen, T., … David, L. (2021). Integrated pseudotime analysis of human pre-implantation embryo single-cell transcriptomes reveals the dynamics of lineage specification. Cell Stem Cell, 28(9), 1625-1640.e6. https://doi.org/10.1016/j.stem.2021.04.027