• Casanova M, Moscatelli M, Chauvière LÉ, Huret C, Samson J, Liyakat Ali TM, Rosspopoff O, Rougeulle C. A primate-specific retroviral enhancer wires the XACT lncRNA into the core pluripotency network in humans. Nat Commun. 2019 Dec 11;10(1):5652.


  • Furlan G, Gutierrez Hernandez N, Huret C, Galupa R, van Bemmel JG, Romito A, Heard E, Morey C, Rougeulle C.  The Ftx Noncoding Locus Controls X Chromosome Inactivation Independently of Its RNA Products. Mol Cell. 2018 Apr 20. pii: S1097-2765(18)30227-2.
  • Ouimette JF, Rougeulle C, Veitia RA. Three-dimensional genome architecture in health and disease.Clin Genet. 2018 Jan 29.
  • Kilens S, Meistermann D, Moreno D, Chariau C, Gaignerie A, Reignier A, Lelièvre Y, Casanova M, Vallot C, Nedellec S, Flippe L, Firmin J, Song J, Charpentier E, Lammers J, Donnart A, Marec N, Deb W, Bihouée A, Le Caignec C, Pecqueur C, Redon R, Barrière P, Bourdon J, Pasque V, Soumillon M, Mikkelsen TS, Rougeulle C, Fréour T, David L.  Parallel derivation of isogenic human primed and naive induced pluripotent stem cells. Nat Commun. 2018 Jan 24;9(1):360



  • Cantone I.,  Bagci H., Dormann D., Dharmalingam G., Nesterova T., Brockdorff N., Rougeulle C., Vallot C., Heard E., Chaligne R., Merkenschlager M., Fisher A.G. Ordered chromatin changes and human X chromosome reactivation by cell fusion-mediated pluripotent reprogramming. Nat Commun. 2016 Aug 10;7:12354.
  • Vallot C.Ouimette JF., Rougeulle C. Establishment of X chromosome inactivation and epigenomic features of the inactive X depend on cellular contexts.  2016 Sep;38(9):869-80​
  • Casanova M.Liyakat Ali T.M., Rougeulle C. Enlightening the contribution of the dark matter to the X chromosome inactivation process in mammals. Semin Cell Dev Biol. 2016 Aug;56:48-57.​
  • Furlan G., Rougeulle C. Function and evolution of the long noncoding RNA circuitry orchestrating X-chromosome inactivation in mammals. Wiley Interdiscip Rev RNA. 2016 Sep;7(5):702-22.​
  • Nguyen LS, Lepleux M, Makhlouf M, Martin C, Fregeac J, Siquier-Pernet K, Philippe A, Feron F, Gepner B, Rougeulle C, Humeau Y, Colleaux L. Profiling olfactory stem cells from living patients identifies miRNAs relevant for autism pathophysiology. Mol Autism. 2016 Jan 8;7:1
  • Ouimette JF, Rougeulle C. How Many Non-coding RNAs Does It Take to Compensate Male/Female Genetic Imbalance?  Adv Exp Med Biol. 2016;886:33-49


  • Vallot C*, Ouimette JF*, Makhlouf M, Féraud O, Pontis J, Côme J, Martinat C, Bennaceur-Griscelli A, Lalande M, Rougeulle C. Erosion of X Chromosome Inactivation in Human Pluripotent Cells Initiates with XACT Coating and Depends on a Specific Heterochromatin Landscape.Cell Stem Cell. 2015 May 7;16(5):533-46.
  • Lazorthes S., Briois S., Vallot C., Aguirrebengoa M., Thuret JY., St. Laurent G., Rougeulle C., Kapranov P., Mann C., Trouche D., and Nicolas E. A vlincRNA participates in senescence maintenance by relieving H2AZ mediated repression at the INK4 locus. Nat Commun. 2015 Jan 20;6:5971.​
  • Chen H., Aksoy I., Gonnot F., Osteil P., Aubry M., Hamela C., Rognard C., Hochard A., Voisin S., Fontaine E., Mure M., Afanassieff M., Cleroux E., Guibert S., Chen J., Vallot C., Acloque H., Genthon C., Donnadieu C., De Vos J., Sanlaville D., Guérin JF., Weber M., Stanton LW., Rougeulle C., Pain B., Bourillot PY., and Savatier P.  Reinforcement of STAT3 activity reprograms human embryonic stem cells to naïve-like pluripotency. Nat Commun. 2015 May 13;6:7095.​


  • Makhlouf M.*, Ouimette JF.*, Oldfield A.*, Navarro P., Neuillet D. and Rougeulle C. A prominent and conserved role for YY1 in Xist transcriptional activation. Nat Commun. 2014 Sep 11;5:4878.




  • Chureau C., Chantalat S., Romito A., Galvani A., Duret L., Avner P. and Rougeulle C. Ftx is a non-coding RNA which affects Xist expression and chromatin structure within the X-inactivation center region. Hum Mol Genet. 2011 Feb 15;20(4):705-18.​


  • Navarro P., Oldfield A., Legoupi J., Festuccia N., Dubois A., Attia M., Schoorlemmer J., Rougeulle C., Chambers I. and Avner P. Molecular coupling of Tsix regulation and pluripotency. 2010 Nov 18;468(7322):457-60.​
  • Mitjavila-Garcia M., Bonnet M.L., Yates F., Haddad R., Oudrhiri N., Féraud O., Magniez A., Vallot C., Makhlouf M., Rougeulle C., Bennaceur-Griscelli A. and Turhan A.G. Partial reversal of the methylation pattern of X-linked gene HUMARA during hematopoietic differentiation of human embryonic stem cells. J Mol Cell Biol. 2010 Oct;2(5):291-8.​
  • Fritsch L, Robin P., Mathieu JRR, Souidi M., Hinaux, H. Rougeulle C., Harel-Bellan A., Ameyar-Zazoua M. and Ait-Si-Ali S. A Subset of the histone H3 lysine 9 methyltransferases Suv39h1/KMT1A, G9a/KMT1C, GLP/KMT1D and SETDB1/KMT1E participate in a multimeric complex. Mol Cell. 2010 Jan 15;37(1):46-56.​


  • Oldfield A. and Rougeulle C. X-plications sur le contrôle de l’inactivation : la régulation du gène Xist.Biofutur 304 : 28-31.
  • Navarro P., Chantalat S., Foglio M., Chureau C., Vigneau S., Clerc P. Avner P. and Rougeulle C. A role for non-coding Tsix transcription in partitioning chromatin domains within the mouse X-inactivation centre. Epigenetics Chromatin. 2009 Jul 20;2(1):8.​
  • Rougeulle C. X inactivation in embryonic stem cells is controlled by pluripotent genes. Med Sci (Paris). 2009 Mar;25(3):234-5.​