Bertrand COSSON
Equipe : Dynamique épigénétique et différenciation cellulaire
Bertrand Cosson is specialized in the regulation of mRNA stability and translation through the cell cycle and development in different organisms including marine animals and mammalian cells. He has in particular deciphered how eIF4E-binding proteins play a critical role in early sea urchin development, and has gained insight into structural features of eIF4E/4E-BP interaction, including in mammals. Furthermore, Bertrand Cosson has acquired a solid expertise in the biochemical approaches that permit the exploration of mRNA deadenylation and the role of the poly(A) tail in the regulation of mRNA translation/stability. Our project aims to define how novel post transcriptional regulations contribute to cell fate by regulating gene expression